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The Ohio State University Medical Center
Department of Psychiatry
http://psychiatry.osu.edu

Home > Research > Current Research > Molecular Neuropsychopharmacology

Molecular Neuropsychopharmacology


Research is focused on understanding the cellular, molecular and genomic substrate(s) of CNS disorders and the underlying mechanisms. A multifaceted approach is used that might utilize studies in whole animals, isolated rains structures,neuronsal cell cultures or artificial systems. Techniques include: animal modeling and treatment; behavioral testing; neuroreceptor, transporter, and enzyme assays, HPLC, RIA, immunoblots; ELISA; PCR, immunohistochemistry; in situ hybridization; imaging; and others.


Current Projects:
1. Neurotrophic factor signaling and neuroplasticity.
2. Opioid systems and nicotine addiction.
3. Regulation of membrane transporters.
4. Molecular mechanisms of GM1 ganglioside’s neurorestorative action in models of Parkinson’s Disease.